Dr. Andrea Darzi, the assistant director of the AUB GRADE center was invited to present on the "sickle cell disease pilot guidelines" at a conference in Rome, Italy on the 24th of November 2016. The RARE- Best practices project, funded by the European Union, organised the conference to disseminate its findings and offer a forum for discussing how this work could contribute to delivering better health decision-making and health policies for rare diseases. Dr. Darzi highlighted how the GRADE methodology can be used to develop and adapt guidelines for rare diseases. The AUB GRADE center took the lead in coordinating the "sickle cell disease pilot guidelines".