The AUB GRADE center conducted a two-day workshop entitled “Development and Adaptation of Practice Guidelines” on December 6 and 7 2018 at the American University of Beirut, Lebanon. The workshop was facilitated by Dr. Elie Akl, director of the AUB GRADE center, Dr. Assem Khamis, research fellow at the Clinical Research Institute in Lebanon, and Dr. Tamara Lotfi, coordinator of the Global Evidence Synthesis Initiative. Sixteen administrators, nurses, physicians, and researchers from multidisciplinary backgrounds participated in the workshop. They represented various universities and medical centers in Lebanon. The program included introduction to guidelines, the use of the GRADE methodology, and practical exercises using the online guideline development tool (GRADEPro).